Decision making in the treatment of gliomas
This overview looks at the role of age, tumour size, performance status and various predictive and prognostic biomarkers in guiding treatment in newly diagnosed and recurrent disease. Download full article
2011
Beyond Survival–what should new cancer drugs have to prove and how?
As our understanding of cancer increases are randomised controlled trials still the way to get the best drugs into use most quickly? Download full article
Jean-Yves Blay: integrating translational and clinical research
Jean-Yves Blay is leading efforts to reshape cancer research so that every trial has a translational element that can build knowledge about the mechanisms driving the disease. Download full article
Adapting services to the age of oral therapies
The increasing use of oral cancer drugs is contributing to a change in the way cancer services are organised, leading to many more patients receiving care in an ambulatory setting. Download full article
New approaches to treating gastro-oesophageal cancer
Robust evidence on the value of neoadjuvant chemotherapy, together with more effective imaging modalities, are opening up new options for gastro-oesophageal cancer. Download full article
International biobanking regulations: the promise and the pitfalls
A single infrastructure for Europe’s rapidly evolving biobanks is urgently needed. But finding agreement on the ethics, language and operating standards is proving quite a challenge. Download full article
The secret behind a successful clinical trial
Good clinical trials are proposed by clinicians, have the potential for real patient benefit and increase knowledge about the disease, says Pinuccia Valagussa, who is dedicated to helping more centres join trials. Download full article
Cutting unnecessary deaths from cervical cancer
Given how preventable cervical cancer is, setting up screening programmes must be a key element in Europe’s cancer strategy. But as this six country initiative is finding out, it takes a lot. Download full article
Hypoxia modification with radiotherapy for bladder cancer
The outcomes in bladder cancer treated with radiotherapy are suboptimal. Recently, Hoskin et al. reported improved survival in patients with bladder cancer treated with radiation therapy with concurrent hypoxia-modification therapy. These results are promising but [more]
An 18-gene signature (ColoPrint) for colon cancer prognosis
ColoPrint is an 18-gene expression signature designed to predict disease relapse in patients with early-stage colorectal cancer (CRC). We discuss the potential impact of ColoPrint on clinical practice, and its contribution to our knowledge of [more]
Newsround
Selected reports edited by Janet Fricker Download full article
A million voices against cancer
The UN General Assembly Special Session on Non-Communicable Diseases this September offers an all-too-rare window of opportunity to push cancer well up the global health agenda. Read more to see how you can help! Download [more]
Ruth Ladenstein: raising standards of care for our young patients
Paediatric oncologists have a well-deserved reputation for collaborating and treating patients within trial protocols, but there are limits to what they can achieve alone. Download full article