trastuzumab
Neoadjuvant trial design: time for a brave new world?
In the NOAH clinical trial, trastuzumab treatment for locally advanced breast cancer, given prior to surgery, was associated with increased complete and overall response rate and improved event free survival.The ability to identify this advantage [more]
Oncology’s successes must not fail the heart
Targeted therapies seek to close down signalling pathways that allow tumours to prosper. But these pathways may also be vital to other clinical functions. With rising concern about collateral cardiac damage from cancer treatment comes [more]
N E W S R O U N D
Selected reports edited by Hannah Brown Download full article
Cardiac side-effects of trastuzumab: lessons learned from targeting cancer pathways
A recent study has found that symptomatic cardiac toxicity may be a little higher in actual practice than in reports from the clinical trial of trastuzumab, and this finding needs to be incorporated into decision [more]
N e w s r o u n d
Selected reports edited by Hannah Brown Download full article
N E W S R O U N D
Selected press reports compiled by the ESO Download full article
Does trastuzumab increase the risk of isolated CNS metastases in patients with breast cancer?
Research shows that brain metastasis of breast cancer may occur more often in women with HER2 overexpression. These patients require more aggressive surveillance to identify disease earlier, and new therapies are needed that can overcome [more]