Controversial issues in managing locally advanced head and neck cancers

Great strides have beenmade inmanaging patients with locally advanced squamous cell cancer of the head and neck over the past 20 years. Novel approaches using chemoradiation (CRT) have improved disease control and quality of life. But controversies remain about how to optimise the use of CRT, including the role for targeted therapies, and how best to manage high-risk patients.

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