Androgen deprivation therapy for prostate cancer: true love or heartbreak?

Jason Efstathiou, William Shipley, Anthony Zietman and Matthew Smith

The addition of hormonal therapy to radiation therapy improves survival inmenwith unfavourable risk prostate cancer.Yet,menwith prostate cancer have higher rates of non-cancer death than the general population andmost will die fromcauses other than their indexmalignancy. Comorbid cardiovascular disease is strongly associatedwith cause of death and this raises the possibility that prostate cancer or its treatment increases cardiovascular disease risk and possiblymortality.

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