Relapsed Hodgkin’s lymphoma: new twist to the standard regimen
Results of a multicentre study show that a sequential high-dose chemotherapy variant of the standard treatment is safe and effective in relapsed Hodgkin’s patients. Download full article
Impact Factor
Lung cancer: spotting the symptoms
New research reveals that lung cancers could be picked up much earlier if only the public and health professionals learnt how to recognise the critical symptoms. Download full article
Sentinel node biopsy gets an excellent report
The latest study on use of the sentinel node biopsy has prompted calls for the procedure to be universally adopted. But can inexperienced teams be trusted to get it right? Download full article
Glioblastoma: two studies herald a new start
Surprise results of a temozolomide trial, and a new marker predicting who will benefit, offer hope for progress in the treatment of a highly aggressive brain tumour. Download full article
Follicular lymphoma: side-lined drug excites new interest
A study showing that follicular lymphoma patients benefit from adding interferon to standard chemotherapy has opened up new avenues for research. Download full article
Minimising radiotherapy in children with rhabdomyosarcoma
US and European paediatric oncologists are finally finding common ground over which patients need potentially damaging aggressive local treatment, and which can be spared. Download full article
Could COX-2s stage a comeback in cancer?
Hopes for a drug that could inhibit colorectal cancer took a knock last year due to revelations of serious side-effects. But a combination therapy may now offer a way forward. Download full article
Neoadjuvant studies offer mixed messages
Three recent papers have failed to confirm any clear benefit of neoadjuvant treatment on overall survival. But its value in minimising the extent of surgery and its potential for greater survival effect using newer drugs [more]
Cancer vaccine for CML shows promise
Vaccines have long been seen as a potentially attractive option for treating cancer. Now a group targeting a peptide that plays a key role in CML think they may be onto a winner. Download full [more]
Has tamoxifen had its day?
Anastrozole is being hailed by some as the new tamoxifen. But many researchers feel there is a great deal more we need to know before we consider casting aside the hormonal treatment that has served [more]
Doctors who shun guidelines get worse results
An unhelpful straightjacket or an essential tool for optimal treatment? Some physicians still trust their own skill and judgement above all else, but new evidence shows that patients do best when their doctors follow consensus [more]
Advanced head and neck cancers
Transatlantic collaboration shows results