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immune checkpoint inhibitors

Management of toxicities related to immunotherapies

Number 86

Grandround 30 May 2019 0

Immunotherapy agents are being used to treat a growing range of cancers, but emerging evidence from randomised trials and clinical practice shows very different patterns of toxicity compared to chemotherapy. Jean-Marie Michot reviews what doctors [more]

With ICIs, the effect of mutations changes with cancer types

News 17 January 2019 0

“Immune checkpoint inhibitor (ICI) treatments benefit some patients with metastatic cancers, but predictive biomarkers are needed”: starting from this premise, a group of researchers of the Memorial Sloan Kettering Cancer Center in New York led [more]

Immunologists Allison and Honjo won the Nobel prize for their work on checkpoints

News 1 October 2018 0

American James Allison and Japanese Tasuku Honjo have been awarded the 2018 Nobel Prize for Physiology or Medicine thanks to their findings leading to recent new approaches in cancer treatment. James Allison, born in Texas [more]

Fatal reactions to immunotherapies are rare, but have diverse causes

News 24 September 2018 0

The most commonly prescribed class of immunotherapies (called ICIs, immune checkpoint inhibitors) are not free from fulminant and fatal toxic side effects; the researchers of the Vanderbilt-Ingram Cancer Center recently evaluated their toxicities, publishing the [more]

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