target

New cancer drugs may not work the way scientists thought

News 14 October 2019 0

Many cancer drugs undergoing clinical trials kill malignant cells by acting on targets different from the one they were intended to hit. This surprising finding warns against poor preclinical characterization of targets and potential drugs [more]

Don’t shoot the driver! It’s about taxonomy more than targets

Number 81

Cutting Edge, Featured 9 March 2018 0

Could tailoring treatments to broad taxonomies work where targeting individual – or even multiple – genetic mutations has not? A growing number of researchers working on specific tumour types and/or across tumours believe this integrative [more]