Ultra-targeted accelerated partial breast irradiation using TARGIT – a cautionary note

Rijiv Sarin

One of the seven ongoing trials of accelerated partial breast irradiation (APBI) has concluded that single-dose intraoperative radiotherapy should be considered as an alternative to protracted whole-breast irradiation. With a median follow up of two years, such conclusions seem premature. Until the risk and pattern of recurrence is reported at longer follow up, APBI should remain experimental.

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