Treatment of triple negative breast cancer
Triple negative breast cancers, as a subgroup, are associated with a poor prognosis. But different subtypes within triple negative disease are associated with different outcomes… Download full article
2011
Reading the signs
The concept of a genomic signature that can define any tumour according to its unique biology has been central to the emerging paradigm of personalised therapy. But how helpful are multi-gene assays in guiding treatment [more]
Think before you ruin your patient’s chance of parenthood
The plight of cancer patients for whom treatment means risking losing the opportunity to have children was taken up in a piece that earned Sławomir Zagórski a BCRA. Download full article
A simple doctor’s quest to improve on today’s treatments
Stan Kaye, head of drug development at the Royal Marsden treasures the moments when a new drug turns up that shows real value. The big challenge is to understand who benefits from what. Download full [more]
Where are the consensus guidelines for women with metastatic disease?
Women with advanced breast cancer can live a full and active life. But median survival is still hovering around three years and progress is frustratingly slow. A new conference now seeks to change this. Download [more]
An advanced oncology degree for busy specialists across the globe
Oncologists wanting to develop and work can find it hard to balance the competing priorities of clinical practice and study. This new online MSc in Advanced Oncology run by the University of Ulm may be [more]
Failure of bevacizumab in early-stage colon cancer
A randomised phase III trial of patients with stage II and III colon cancer showed no benefit of adding bevacizumab to standard adjuvant oxaliplatin plus fluorouracil and leucovorin. Despite suggestive evidence of a short-term benefit, [more]
Ultra-targeted accelerated partial breast irradiation using TARGIT a cautionary note
One of the seven ongoing trials of accelerated partial breast irradiation (APBI) has concluded that single-dose intraoperative radiotherapy should be considered as an alternative to protracted whole-breast irradiation. With a median follow up of two [more]
NEWSROUND
Selected reports edited by Janet Fricker Download full article
Our role in moulding the image of cancer
The mass media and high-profile cancer campaigns have a major influence in shaping public perceptions of cancer. But who can influence the media? Download full article
Klaus Meier: together we can offer the best of both worlds
As more cancers are treated as chronic diseases, and cancer regimens become more complex, difficulties with adherence and the potential for damaging interactions are steadily rising. Download full article
Management of metastatic pancreatic cancer: current strategies and future directions
Despite recent progress, pancreatic cancer remains one of the worst cancer diagnoses. Malcolm Moore reviews current management and considers future progress. Download full article
Promoting genetic literacy: cancer control in the BRCA era
As more is learned about inherited genetic mutations that make cancers more likely, there is an acute need to give those who live with the mutated genes clear information and accurate advice. Download full article